The BMCS Mastering MedChem VI:

6th RSC-BMCS symposium on

mastering medicinal chemistry

 

Tuesday & Wednesday, 29th & 30th June 2021

(two afternoon sessions)

 

 

A virtual event

Registration is closed

closed at 12 noon BST on Friday, 25th June

 

Twitter hashtag #MasterMedChem21

 

Downloads and Links
Third announcement

Second announcement

First announcement and call for posters

 

RSC special offer on affiliate membership - follow this link to see below

Link to the BMCS's COVID-19 statement

 

BMCS website

RSC website

 

Synopsis
Mastering Medicinal Chemistry VI is the latest in an ongoing series of conferences intended to provide expert advice and guidance to new practitioners in the field of drug discovery. It has been said that "there are two types of drug discovery programmes: those that hit serious problems and those that are going to hit serious problems".

Anticipating and preparing for such problems thus accelerates the delivery of new medicines: this event featured presentations from experienced 'drug-hunters' in both industry and academia, who talked about the challenges faced in modern drug discovery, and shared best practice common to all successful medicinal chemists.

 

Features of the Meeting
The meeting included:
• Two afternoon sessions
• Relevant trade exhibition
• Poster display throughout the meeting
 

Call for Posters
Posters were invited for display throughout the meeting. The closing date for abstract submission was 28th May 2021. 

 

Programme

All timings are UK time (BST)

Where the presentation title is highlighted in blue, you may download a .pdf of the speaker's slides.

 

Tuesday, 29th June

13.00

Welcome

Session Chair:  Nadia Ahmad, Charles River, UK

13.10

The importance of conformation in the structure-based design of selective CaMK1 inhibitors
Sam Butterworth, Manchester University, UK

13.55Exhibitor talk : Activate Scientific: chemistry services for drug discovery

Declan Wolverson, Activate Scientific

14.00

Development of a potent class of small molecule inhibitors of the MDM2-p53 protein-protein interaction
Ian Hardcastle, Newcastle University, UK

 

14.45

Session Chair:  Gordon Saxty, Fidelta, UK

Flash poster session 1 (using GoToWebinar)

14.45Stapled peptide-drug conjugates with antimicrobial activity
Josephine S. Gaynord, University of Cambridge, UK
14.50Analgesic and antidepressent activity of Harmine hydrazone derivatives and molecular docking
Dmitriy Berillo, Kazakh National Medicinal University, Kazakhstan

15.00

Refreshment break and poster viewing (using Grapevine)

 

15.40Exhibitor talk :  Design, screening and synthesis of lead-like libraries derived from 3D-fragments

Tammy Warnock, Liverpool ChiroChem

15.45

Practical drug discovery using explainable AI
Al Dossetter, MedChemica, UK

16.30

Close

 

Wednesday, 30th June

13.00

Welcome

Session Chair:  Dave Alker, David Alker Associates, UK

13.10

New treatments for inflammatory diseases:  from idea to the clinic
Rhona Cox, AstraZeneca, Sweden

13.55Exhibitor talk:  Flexible flash chromatography solutions – with insights from Dr James Hitchin at Charnwood Molecular Ltd
Mark Dodsworth, Teledyne ISCO

14.00

The challenges of drug discovery in Chagas disease
Silvia Gonzalez del Valle, GlaxoSmithKline, Spain

 

14.45

Session Chair:  Joe Sweeney, University of Lancaster, UK

Flash poster session 2 (using GoToWebinar)

14.45Exploiting the biophysical sweet spot in fragment-based drug discovery chromatography
Thomas Pesnot, Concept Life Sciences, UK
14.50A ubiquitin activating enzyme as a novel therapeutic target for leishmaniasis
Daniel Harris, University of Glasgow, UK

15.00

Refreshment break and poster viewing (using Grapevine)

 

15.40Exhibitor talk : BLD - accelerating drug discovery

Andrew Fraser, BLD Pharmatech

15.45

The discovery of erdafitinib, a selective FGFR inhibitor
Chris Murray, Astex Pharmaceuticals, UK

16.30

Close

 

Registration and Students
Registration closed at 12 noon BST on Friday, 25th June

 

£50  Member* of the RSC

£75  Non-member
£25  RSC student** member
£37  Student** non-member
 

*  Member is a paid-up member of the RSC.

** Student is undergraduate or post-graduate, not post-doc
 

Cancellation Policy
In the event of cancellation before 16th June 2021, 80% of the fee paid will be refunded. Cancellations must be received in writing. Refunds will not be possible after that date although substitutions are possible at any time. In the unlikely event of cancellation of the meeting, fees paid will be refunded in full. Acknowledgements will be sent within two weeks.

 

Exhibition Opportunities
We were offering two alternative packages to our valued supporters.

Exhibitor Sponsorship Package
Your organisation's name and weblink on this webpage
Your logo in the rolling slides shown at the event and a web-linked logo in the electronic delegate handbook
An A4 promotional page in the electronic delegate handbook
Charge is £60, excludes delegate registration

Speaker Sponsorship Package -
sorry, fully booked
All features in the above Exhibitor Sponsorship Package, plus:
- a pre-recorded speaker slot of 5 minutes max, 5 slides max, to be shown at a time to be determined
Charge is £150, excludes delegate registration (limited availability)

 

Confirmed Exhibitor Speakers

Activate Scientific

BLD Pharmatech

Liverpool ChiroChem

Teledyne ISCO

 

Confirmed Exhibitor Sponsors

Apex Molecular

Biotage AB, from Sweden

Reach Separations

 

RSC Special Offer on Membership

 

 

We know that not everyone in the audience is a member of the Royal Society of Chemistry and there may be several reasons for this, but right now the RSC are offering free Affiliate membership to anyone who attends one of our online events. If you have ever considered joining but haven’t got around to it, or are not sure what you could get out of being a member, then maybe now is the time to sign up as an Affiliate for free and try it out.

Affiliate membership does not need a degree transcript or CV, simply go to
rsc.li/affiliate and use the discount code IG100 to join - you can then become a member of our Interest Group, the BMCS, and keep up to date with all of our events and activities!

Affiliate membership offers:
- Free membership of one Interest Group*
- Depending on where you are in the world, automatic membership of an RSC Local Section - - Ten free RSC journal article downloads a year, and 35% off RSC books
- Online access to Chemistry World
- Access to careers resources and webinars, and discounts for accredited training courses
- Support from the Chemists’ Community Fund
- Discounts on travel, insurance, lifestyle and publications.
* You may wish to choose the BMCS (Biological and Medicinal Chemistry Sector)!

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Sponsors
Sponsors were encouraged to support this event, which helped us to offer inexpensive registration fees to young chemists.  We are grateful to our confirmed sponsors:

   

 

 

 

 

We are grateful to EFMC, RSC Chemical Biology, and RSC Medicinal Chemistry for supporting this event

 

 

 

Organising Committee
Nadia Ahmad (chair), Charles River
David Alker, Chemistry Recruitment Consultant
Gordon Saxty (treasurer), Fidelta
Joe Sweeney, Lancaster University

 

Secretariat Contact
Cathy Hill, Cathy Hill Events, The Old School, The Street, Stowlangtoft, Bury St Edmunds IP31 3JN, UK
E-mail:       cathy@cathyhillevents.co.uk

 

Registration is closed

closed at 12 noon BST on Friday, 25th June

 


 

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